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Whereas very low-depend MBL not often progresses to CLL, substantial-count MBL progresses to CLL demanding therapy in a rate of one% to 2% per annum. High-depend MBL is distinguished from Rai 0 CLL based upon whether the B-mobile count is earlier mentioned or down below 5 × 109/L. Despite the fact that folks with each large-depend MBL and CLL Rai